An Immunogenic Cell Death-Related Classification Predicts Prognosis and Response to Immunotherapy in Glioblastoma

نویسندگان

چکیده

To investigate the immunogenic Cell Death gene’s potential mechanism and prognostic value in glioblastoma. Information on GBM samples from The Cancer Genome Atlas database was downloaded, ICD genes were obtained, genotyping, integrated bioinformatics to verify of finally, model construction. Two subtypes associated with gene obtained by consensus clustering, high subtype (risk) group poor prognosis, mutations PTEN gene, stromal score, immune score. We also constructed a new classification system for based characteristics. This study is first use cell death genotyping successfully build model.

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ژورنال

عنوان ژورنال: Journal of Biosciences and Medicines

سال: 2023

ISSN: ['2327-509X', '2327-5081']

DOI: https://doi.org/10.4236/jbm.2023.118009